abstract：:Fetomodulin (FM) was previously shown to be a surface marker protein of parietal endoderm by in vitro differentiation of F9 embryonal carcinoma cells and by immunohistochemistry of in vivo embryos. BALB/3T3 and sarcoma S180 cells of the mouse were also shown to possess a protein which was indistinguishable from FM by ...

journal_title：Developmental biology

authors： Imada S,Yamaguchi H,Nagumo M,Katayanagi S,Iwasaki H,Imada M

更新日期：1990-07-01 00:00:00

abstract：:I report on the synthesis of fibronectin in the developing chick Müllerian duct mesenchymal cells. Before the differentiation of female chick Müllerian duct, the amount of fibronectin in the cells of the right duct is 44% lower than in the left duct. While after differentiation, the amount of fibronectin in the right ...

journal_title：Developmental biology

authors： Teng CS

更新日期：1990-07-01 00:00:00

abstract：:The large ampullate glands of the orb-web spider, Nephila clavipes provide massive amounts of fibroin throughout the lifetime of the adult female. We have developed methods to culture the glands and manipulate their biosynthetic activity. This has allowed us to monitor a series of molecular events that precede silk pr...

journal_title：Developmental biology

authors： Candelas GC,Arroyo G,Carrasco C,Dompenciel R

更新日期：1990-07-01 00:00:00

abstract：:The relationship between ascorbic acid concentration and cellular transport mechanisms was studied in chicken embryos (Gallus gallus domesticus). Unincubated (Day 0) fertile eggs did not contain detectable levels of ascorbic acid as assayed by high performance liquid chromatography with electrochemical detection. Howe...

journal_title：Developmental biology

authors： Wilson JX

更新日期：1990-06-01 00:00:00

abstract：:Vimentin expression in the lens is striking due to the reported mesenchymal preference of vimentin and the epithelial origin of the lens. The amount of chicken vimentin mRNA levels determined by Northern blot analysis increased 3-fold from 7 to 14 days of embryonic lens development and then decreased 10-fold at 16 day...

journal_title：Developmental biology

authors： Sax CM,Farrell FX,Zehner ZE,Piatigorsky J

更新日期：1990-05-01 00:00:00

abstract：:P19 embryonal carcinoma cells are multipotential stem cells that differentiate into striated muscle as well as some other cell types when aggregated and exposed to dimethyl sulfoxide (DMSO). Immunofluorescence experiments using monospecific antibodies indicated that the majority of muscle cells were mononucleate and c...

journal_title：Developmental biology

authors： Rudnicki MA,Jackowski G,Saggin L,McBurney MW

更新日期：1990-04-01 00:00:00

abstract：:We have investigated sensillum development in Drosophila embryos homozygous for mutations in the locus string (stg). In these embryos, cell division is blocked following blastoderm formation. This permits a study of the differentiative fate of undivided precursor cells, in particular those giving rise to the larval se...

journal_title：Developmental biology

authors： Hartenstein V,Posakony JW

更新日期：1990-03-01 00:00:00

abstract：:Interstitial cell migration was characterized in Hydra vulgaris (formerly H. attenuata) and the effects of axial position and tissue injury on migration were investigated. Migrating cells were labeled with the thymidine analog, bromodeoxyuridine, and grafted into unlabeled host polyps. Alternatively, cells were labele...

journal_title：Developmental biology

authors： Teragawa CK,Bode HR

更新日期：1990-03-01 00:00:00

abstract：:We have used amphibian gastrulation as a model system to study the action of the extracellular matrix (ECM) glycoprotein tenascin on mesodermal cell migration. Tenascin function was assayed in vitro during spreading of isolated cells from the dorsal marginal zone (DMZ) and during cell migration from DMZ explants. Plas...

journal_title：Developmental biology

authors： Riou JF,Shi DL,Chiquet M,Boucaut JC

更新日期：1990-02-01 00:00:00

abstract：:Temporal and spatial aspects of floral determination in seedling terminal buds of the qualitative short-day plant Pharbitis nil were examined using a grafting assay. Floral determination in the terminal buds of 6-day-old P. nil seedlings is rapid; by 9 hr after the end of a 14-hr inductive dark period more than 50% of...

journal_title：Developmental biology

authors： Larkin JC,Felsheim R,Das A

更新日期：1990-02-01 00:00:00

abstract：:Two populations of blastomeres become positionally distinct during fourth cleavage in the mouse embryo; the inner cells become enclosed within the embryo and the outer cells form the enclosing layer. The segregation of these two cell populations is important for later development, because it represents the initial ste...

journal_title：Developmental biology

authors： Sutherland AE,Speed TP,Calarco PG

更新日期：1990-01-01 00:00:00

abstract：:The survival effects of brain-derived neurotrophic factor (BDNF) on the ganglion cells of the chick retina were studied in vitro at different embryonic ages. We found these effects to be strongly age-dependent: at E5, when the first ganglion cell axons have crossed the optic chiasm, but not yet reached the tectum, gan...

journal_title：Developmental biology

authors： Rodriguez-Tébar A,Jeffrey PL,Thoenen H,Barde YA

更新日期：1989-12-01 00:00:00

abstract：:Serendipity delta (sry delta) is a member of a set of Drosophila zinc finger protein genes showing maximal transcription during oogenesis. By using transformant lines, we monitored the zygotic expression of the sry delta gene and characterized some biochemical properties of a sry delta/beta-galactosidase fusion protei...

journal_title：Developmental biology

authors： Payre F,Yanicostas C,Vincent A

更新日期：1989-12-01 00:00:00

abstract：:The growing pollen tubes of tomato and tobacco were exposed to electrical fields and the effect on the direction of growth was measured. They responded by turning toward the positive electrode (anode) and gave a detectable response in fields as small as 0.1 mV/tube diameter. The sites of germination of tobacco pollen ...

journal_title：Developmental biology

authors： Wang C,Rathore KS,Robinson KR

更新日期：1989-12-01 00:00:00

abstract：:In the absence of maternal expression of the pecanex gene, the embryo develops severe hyperneuralization similar to that characteristic of Notch mutant embryos. We have extended a previous molecular analysis of the chromosomal interval that encompasses pecanex by using additional deficiencies to localize the locus on ...

journal_title：Developmental biology

authors： LaBonne SG,Sunitha I,Mahowald AP

更新日期：1989-11-01 00:00:00

abstract：:The embryonic chick face is composed of a series of facial primordia, epithelium-covered buds of mesenchyme, which surround the presumptive mouth. The protruding adult upper beak containing the prenasal cartilage is formed from the frontonasal mass, the paired maxillary primordia form the sides of the face, while the ...

journal_title：Developmental biology

authors： Richman JM,Tickle C

更新日期：1989-11-01 00:00:00

abstract：:The embryonic vertebrate heart consists of two epithelia: the myocardium and endothelium, separated by the myocardial basement membrane (MBM). The myocardium has been shown to induce endothelial transformation into prevalvular mesenchyme in a temporally and site restricted manner. Previously, we hypothesized that the ...

journal_title：Developmental biology

authors： Mjaatvedt CH,Markwald RR

更新日期：1989-11-01 00:00:00

abstract：:The role of the wound epithelium in amphibian limb regeneration is not understood. We showed previously that monoclonal antibody (mAb) WE3 stains the wound epithelium but not skin epidermis, suggesting that the WE3 antigen may be a marker for, or be important in, the function of the wound epithelium. In the present st...

journal_title：Developmental biology

authors： Goldhamer DJ,Tomlinson BL,Tassava RA

更新日期：1989-10-01 00:00:00

abstract：:Fertilized eggs of the leech Helobdella triserialis undergo a cytoplasmic reorganization which generates domains of nonyolky cytoplasm, called teloplasm, at the animal and vegetal poles. The segregation of teloplasm to one cell of the eight-cell embryo is responsible for a unique developmental fate of that cell, i.e.,...

journal_title：Developmental biology

authors： Astrow SH,Holton B,Weisblat DA

更新日期：1989-10-01 00:00:00

abstract：:The cardiac neural crest contains ectomesenchymal and neural anlagen that are necessary for normal heart development. It is not known whether other regions of the neural crest are capable of supporting normal heart development. In the experiments reported herein, quail donor embryos provided cardiac, trunk, or mesence...

journal_title：Developmental biology

authors： Kirby ML

更新日期：1989-08-01 00:00:00

abstract：:We present a genetic, developmental and molecular analysis of lethal(1)discs large-1[l(1)d.lg-1; Stewart et al., 1972], an oncogene of Drosophila. Mutations in this gene cause the imaginal discs to grow by cell proliferation beyond their normal final size, transform into solid tumors, fuse with one another and the bra...

journal_title：Developmental biology

authors： Woods DF,Bryant PJ

更新日期：1989-07-01 00:00:00

abstract：:When a posterior fragment of the chick's marginal zone (PM) was exchanged with equal sized lateral marginal zone fragment (LM), of the same blastoderm, its capacity to initiate an ectopic primitive streak (PS) was found to be both size and stage dependent. Good correlation was demonstrated between the areas of PM frag...

journal_title：Developmental biology

authors： Eyal-Giladi H,Khaner O

更新日期：1989-07-01 00:00:00

abstract：:We have isolated a nonneuronal cell line from Xenopus retinal neuroepithelium (XR1 cell line). On the basis of immunocytochemical characterization using monoclonal antibodies generated in our laboratory as well as several other glial-specific antibodies, we have established that the XR1 cells are derived from embryoni...

journal_title：Developmental biology

authors： Sakaguchi DS,Moeller JF,Coffman CR,Gallenson N,Harris WA

更新日期：1989-07-01 00:00:00

abstract：:In amphibians, the composition and pattern of expression of the myosin heavy chain (myHC) gene family are mostly unknown. To understand better the regulation of this complex family, we screened cDNA libraries from swimming tadpole and adult leg muscle RNA and have isolated and partially sequenced clones for several my...

journal_title：Developmental biology

authors： Radice GP,Malacinski GM

更新日期：1989-06-01 00:00:00

abstract：:Cell polarity is thought to be required for the efficient production of nascent blastocoele fluid, which begins at the 16-cell stage of mouse preimplantation development. In this study the 4-cell/16-cell blastomere heterokaryon was used to test the hypothesis that solute transport across the apical membrane domain ind...

journal_title：Developmental biology

authors： Wiley LM,Obasaju MF

更新日期：1989-06-01 00:00:00

abstract：:To examine the possible role of homeo box genes in murine development we have studied the structure and expression pattern of Hox-2.5, a newly isolated homeo box gene that maps to the left end of the mouse Hox-2 locus on chromosome 11. The sequence of the Hox-2.5 homeo box has been determined. It is highly homologous ...

journal_title：Developmental biology

authors： Bogarad LD,Utset MF,Awgulewitsch A,Miki T,Hart CP,Ruddle FH

更新日期：1989-06-01 00:00:00

abstract：:Epi 1, a monoclonal antibody, was generated against an epidermal specific epithelial antigen; it does not stain neural epithelium. We have used Epi 1 as a marker to determine when the spatial patterns delineating neural from nonneural epithelium become established. We used ventral ectoderm in a sandwich assay to show ...

journal_title：Developmental biology

authors： Savage R,Phillips CR

更新日期：1989-05-01 00:00:00

abstract：:A glycoprotein from the liver, which shares epitopes with chorion (egg envelope or zona pellucida) glycoproteins, is present only in the spawning female fish, Oryzias latipes, under natural conditions. This spawning female-specific (SF) substance is distinct from vitellogenin but closely resembles a major glycoprotein...

journal_title：Developmental biology

authors： Hamazaki TS,Nagahama Y,Iuchi I,Yamagami K

更新日期：1989-05-01 00:00:00

abstract：:Maize leaves are divided into repeated longitudinal units consisting of vascular tissue, bundle sheath (BS), and mesophyll (M) cells. We have carried out a cell lineage analysis of these cell types using six spontaneous striping mutants of maize. We show that certain cell division patterns are preferentially utilized,...

journal_title：Developmental biology

authors： Langdale JA,Lane B,Freeling M,Nelson T

更新日期：1989-05-01 00:00:00

abstract：:During mammalian spermiogenesis transitional proteins and protamines replace histones on the DNA as the chromatin condenses. While previous studies suggested that histone genes are inactive postmeiotically, we have shown both by steady-state RNA analysis and nuclear run-off transcription assays that histone 2b (H2b) t...

journal_title：Developmental biology

authors： Moss SB,Challoner PB,Groudine M

更新日期：1989-05-01 00:00:00

abstract：:In embryos of Patella vulgata at the 32-cell stage, one of the four vegetally located macromeres makes contacts with overlying animal micromeres. As a result, this macromere (designated 3D) divides significantly later than the other macromeres and forms the mesodermal stem cell 4d. Shortly before and during this inter...

journal_title：Developmental biology

authors： Kühtreiber WM,van Dongen CA

更新日期：1989-04-01 00:00:00

abstract：:A monoclonal antibody (MAb No. 25-16), raised against purified cortical secretory vesicles (CVs) from the eggs of Strongylocentrotus purpuratus, has been used to identify a previously uncharacterized CV-derived polypeptide component of the sea urchin fertilization envelope (FE). MAb No. 25-16, an IgG1, bound to a grou...

journal_title：Developmental biology

authors： Vater CA,Jackson RC

更新日期：1989-03-01 00:00:00

abstract：:Nerve and muscle development was studied in paralysé mutant mice. The mutant phenotype is first recognizable 6-7 days after birth (PN 6-PN 7) as cessation of muscle growth and weakness and incoordination of movement. Mutant animals die between 2 and 3 weeks of age. Muscle fibers from paralysé mutants had a unimodal di...

journal_title：Developmental biology

authors： Blondet B,Duxson MJ,Harris AJ,Melki J,Guénet JL,Pinçon-Raymond M,Rieger F

更新日期：1989-03-01 00:00:00

abstract：:Catecholaminergic cells are transiently present during development of the fetal murine bowel. These transient catecholaminergic (TC) cells appear at Day E10, but by Day E13 can no longer be detected. In order to evaluate the hypothesis that these cells are the precursors of enteric neurons, we investigated the possibi...

journal_title：Developmental biology

authors： Baetge G,Gershon MD

更新日期：1989-03-01 00:00:00

abstract：:Type II collagen is a major component of hyaline cartilage, and has been suggested to be causally involved in promoting chondrogenesis during embryonic development. In the present study we have performed an immunohistochemical analysis of the distribution of type II collagen during several early stages of embryonic ch...

journal_title：Developmental biology

authors： Kosher RA,Solursh M

更新日期：1989-02-01 00:00:00

abstract：:In this paper I sought to determine how the expression of differentiated traits of chick retinal pigmented epithelial (RPE) cells in vitro can be modulated by varying both the biochemical and the spatial complexity, and the mechanical properties, of the growth substratum. I have used glass derivatized with proteins of...

journal_title：Developmental biology

authors： Opas M

更新日期：1989-02-01 00:00:00

abstract：:To examine the role of postsynaptic activity in regulating the rate of neuromuscular synapse elimination, contractile activity of neonatal rabbit soleus muscles was decreased by chronic superfusion of alpha-bungarotoxin (alpha-BGT) over their surfaces. Superfusion was begun at 6 days postnatal and continued for a vari...

journal_title：Developmental biology

authors： Callaway EM,Van Essen DC

更新日期：1989-02-01 00:00:00

abstract：:A series of chimeras was generated by injecting single normal, parthenogenetic, or androgenetic blastomeres carrying transgenic markers under the zona pellucida of nontransgenic eight-cell embryos. These chimeras were cultured to the blastocyst stage and sectioned, and the transgenic component was detected by in situ ...

journal_title：Developmental biology

authors： Thomson JA,Solter D

更新日期：1989-02-01 00:00:00

abstract：:Monoclonal antibodies have been generated to determine the fate of sperm-specific surface components of the sea urchin, Arbacia punctulata, subsequent to gamete fusion. Monoclonal antibody-7 (MAB-7) reacted with two polypeptide bands having apparent molecular masses of 33 and 35 kDa derived from the sperm plasma membr...

journal_title：Developmental biology

authors： Longo FJ

更新日期：1989-01-01 00:00:00

abstract：:The extracellular matrix of Xenopus laevis oocytes was analyzed before and after meiotic maturation using quick-freeze, deep-etch, rotary-shadow electron microscopy. The perivitelline space (PS) of the meiotically immature oocyte contains a filamentous network which connects microvilli (MV) and follicle cell macrovill...

journal_title：Developmental biology

authors： Larabell CA,Chandler DE

更新日期：1989-01-01 00:00:00